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Bulk and Surface Acoustic Wave Biosensors for Milk Analysis

Länge, Kerstin 1
1 Institut für Mikrostrukturtechnik (IMT), Karlsruher Institut für Technologie (KIT)

Abstract:

Milk and dairy products are common foods and, therefore, are subject to regular controls. Such controls cover both the identification and quantification of specific components and the determination of physical parameters. Components include the usual milk ingredients, mainly carbohydrates, proteins, and fat, and any impurities that may be present. The latter range from small molecules, such as drug residues, to large molecules, e.g., protein-based toxins, to pathogenic microorganisms. Physical parameters of interest include viscosity as an indicator of milk gelation. Bulk and surface acoustic wave sensors, such as quartz crystal microbalance (QCM) and surface acoustic wave (SAW) devices, can principally be used for both types of analysis, with the actual application mainly depending on the device coating and the test format. This review summarizes the achievements of acoustic sensor devices used for milk analysis applications, including the determination of physical liquid parameters and the detection of low- and high-molecular-weight analytes and microorganisms. It is shown how the various requirements resulting from the respective analytes and the complex sample matrix are addressed, and to what extent the analytical demands, e.g., with regard to legal limits, are met.


Verlagsausgabe §
DOI: 10.5445/IR/1000150548
Veröffentlicht am 14.09.2022
Originalveröffentlichung
DOI: 10.3390/bios12080602
Scopus
Zitationen: 13
Web of Science
Zitationen: 9
Dimensions
Zitationen: 14
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Mikrostrukturtechnik (IMT)
Publikationstyp Zeitschriftenaufsatz
Publikationsmonat/-jahr 08.2022
Sprache Englisch
Identifikator ISSN: 2079-6374
KITopen-ID: 1000150548
HGF-Programm 43.35.02 (POF IV, LK 01) Functionality of Soft Matter and Biomolecular Systems
Erschienen in Biosensors
Verlag MDPI
Band 12
Heft 8
Seiten 602
Bemerkung zur Veröffentlichung Gefördert durch den KIT-Publikationsfonds
Vorab online veröffentlicht am 05.08.2022
Schlagwörter bulk acoustic wave; surface acoustic wave; quartz crystal microbalance; EMPAS; milk; proteins; toxins; drug residues; pathogens; lab-on-a-chip
Nachgewiesen in Dimensions
Web of Science
Scopus
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