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The impact of tumor metabolic activity assessed by $^{18}$F-FET amino acid PET imaging in particle radiotherapy of high-grade glioma patients

Waltenberger, Maria; Furkel, Jennifer; Röhrich, Manuel; Salome, Patrick; Debus, Charlotte 1; Tawk, Bouchra; Gahlawat, Aoife Ward; Kudak, Andreas; Dostal, Matthias; Wirkner, Ute; Schwager, Christian; Herold-Mende, Christel; Combs, Stephanie E.; König, Laila; Debus, Jürgen; Haberkorn, Uwe; Abdollahi, Amir; Knoll, Maximilian
1 Scientific Computing Center (SCC), Karlsruher Institut für Technologie (KIT)

Abstract:

Selective uptake of (18)F-fluoro-ethyl-tyrosine ($^{18}$F-FET) is used in high-grade glioma (HGG) to assess tumor metabolic activity via positron emission tomography (PET). We aim to investigate its value for target volume definition, as a prognosticator, and associations with whole-blood transcriptome liquid biopsy (WBT lbx) for which we recently reported feasibility to mirror tumor characteristics and response to particle irradiation in recurrent HGG (rHGG).


Verlagsausgabe §
DOI: 10.5445/IR/1000151789
Veröffentlicht am 28.10.2022
Originalveröffentlichung
DOI: 10.3389/fonc.2022.901390
Scopus
Zitationen: 1
Web of Science
Zitationen: 1
Dimensions
Zitationen: 1
Cover der Publikation
Zugehörige Institution(en) am KIT Scientific Computing Center (SCC)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2022
Sprache Englisch
Identifikator ISSN: 2234-943X
KITopen-ID: 1000151789
HGF-Programm 46.21.04 (POF IV, LK 01) HAICU
Erschienen in Frontiers in Oncology
Verlag Frontiers Media SA
Band 12
Seiten Art.Nr. 901390
Vorab online veröffentlicht am 20.09.2022
Nachgewiesen in Dimensions
Web of Science
Scopus
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