The impact of tumor metabolic activity assessed by $^{18}$F-FET amino acid PET imaging in particle radiotherapy of high-grade glioma patients
Abstract:
Selective uptake of (18)F-fluoro-ethyl-tyrosine ($^{18}$F-FET) is used in high-grade glioma (HGG) to assess tumor metabolic activity via positron emission tomography (PET). We aim to investigate its value for target volume definition, as a prognosticator, and associations with whole-blood transcriptome liquid biopsy (WBT lbx) for which we recently reported feasibility to mirror tumor characteristics and response to particle irradiation in recurrent HGG (rHGG).
| Zugehörige Institution(en) am KIT | Scientific Computing Center (SCC) |
| Publikationstyp | Zeitschriftenaufsatz |
| Publikationsjahr | 2022 |
| Sprache | Englisch |
| Identifikator | ISSN: 2234-943X KITopen-ID: 1000151789 |
| HGF-Programm | 46.21.04 (POF IV, LK 01) HAICU |
| Erschienen in | Frontiers in Oncology |
| Verlag | Frontiers Media SA |
| Band | 12 |
| Seiten | Art.Nr. 901390 |
| Vorab online veröffentlicht am | 20.09.2022 |
| Nachgewiesen in | Dimensions Scopus Web of Science |