Analyte sensing with unselectively binding synthetic receptors: virtues of time-resolved supramolecular assays
Prabodh, Amrutha
1; Sinn, Stephan 1; Biedermann, Frank 1
1 Institut für Nanotechnologie (INT), Karlsruher Institut für Technologie (KIT)
1; Sinn, Stephan 1; Biedermann, Frank 11 Institut für Nanotechnologie (INT), Karlsruher Institut für Technologie (KIT)
Abstract:
The cross-reactivity to many analytes is one major limitation of most synthetic receptors (SRs) known so far. Herein, we show that through time-resolved competitive binding assays, even unselectively binding SRs can be utilized for analyte distinction and quantification. Furthermore, our methodology has also been applied to analyte mixtures and can be used in a microplate format.
| Zugehörige Institution(en) am KIT | Institut für Nanotechnologie (INT) |
| Publikationstyp | Zeitschriftenaufsatz |
| Publikationsdatum | 15.12.2022 |
| Sprache | Englisch |
| Identifikator | ISSN: 1359-7345, 1364-548X KITopen-ID: 1000154725 |
| HGF-Programm | 43.31.02 (POF IV, LK 01) Devices and Applications |
| Erschienen in | Chemical Communications |
| Verlag | Royal Society of Chemistry (RSC) |
| Band | 58 |
| Heft | 100 |
| Seiten | 13947–13950 |
| Vorab online veröffentlicht am | 30.11.2022 |
| Nachgewiesen in | Scopus OpenAlex Web of Science Dimensions |