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Phytochemical Composition and Antioxidant, Anti-Acetylcholinesterase, and Anti-α-Glucosidase Activity of Thymus carnosus Extracts: A Three-Year Study on the Impact of Annual Variation and Geographic Location

Martins-Gomes, Carlos; Steck, Jan 1; Keller, Judith 1; Bunzel, Mirko 1; Santos, João A.; Nunes, Fernando M.; Silva, Amélia M.
1 Institut für Angewandte Biowissenschaften (IAB), Karlsruher Institut für Technologie (KIT)

Abstract:

Thymus carnosus Boiss. is a near-threatened species, and, as for many species, its potential for medicinal purposes may be lost if measures towards plant protection are not taken. A way of preserving these species is to increase knowledge about their medicinal properties and economic potential. Thus, with the objective of studying the potentiality of introducing T. carnosus as a crop, the stability of the phytochemical profile of T. carnosus was studied during a period of three years by comparing the phytochemical profile of extracts obtained from plants harvested in two different edaphoclimatic locations, as well as by comparing the respective bioactivities, namely, antioxidant, antidiabetic, antiaging, and neuroprotective activities. It was reported, for the first time, the effect of annual variation and geographic location in the phytochemical composition of aqueous decoction and hydroethanolic extracts of T. carnosus. In addition, the presence of two salvianolic acid B/E isomers in T. carnosus extracts is here described for the first time. Despite the variations in phytochemical composition, according to harvesting location or year, T. ... mehr


Verlagsausgabe §
DOI: 10.5445/IR/1000160306
Veröffentlicht am 10.07.2023
Originalveröffentlichung
DOI: 10.3390/antiox12030668
Scopus
Zitationen: 5
Web of Science
Zitationen: 3
Dimensions
Zitationen: 5
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Angewandte Biowissenschaften (IAB)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2023
Sprache Englisch
Identifikator ISSN: 2076-3921
KITopen-ID: 1000160306
Erschienen in Antioxidants
Verlag MDPI
Band 12
Heft 3
Seiten Art.-Nr.: 668
Vorab online veröffentlicht am 08.03.2023
Schlagwörter antioxidant activity; neuroprotective potential; anti-diabetic potential; Thymus carnosus Boiss.; phytochemical profile; climate variability
Nachgewiesen in Scopus
Dimensions
Web of Science
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