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Simultaneous fermentation and enzymatic biocatalysis—a useful process option?

Oehlenschläger, Katharina; Schepp, Emily 1; Stiefelmaier, Judith; Holtmann, Dirk 1; Ulber, Roland
1 Institut für Bio- und Lebensmitteltechnik (BLT), Karlsruher Institut für Technologie (KIT)

Abstract:

Biotransformation with enzymes and de novo syntheses with whole-cell biocatalysts each have specific advantages. These can be combined to achieve processes with optimal performance. A recent approach is to perform bioconversion processes and enzymatic catalysis simultaneously in one-pot. This is a well-established process in the biorefinery, where starchy or cellulosic material is degraded enzymatically and simultaneously used as substrate for microbial cultivations. This procedure leads to a number of advantages like saving in time but also in the needed equipment (e.g., reaction vessels). In addition, the inhibition or side-reaction of high sugar concentrations can be overcome by combining the processes. These benefits of coupling microbial conversion and enzymatic biotransformation can also be transferred to other processes for example in the sector of biofuel production or in the food industry. However, finding a compromise between the different requirements of the two processes is challenging in some cases. This article summarises the latest developments and process variations.


Verlagsausgabe §
DOI: 10.5445/IR/1000171579
Veröffentlicht am 13.06.2024
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Bio- und Lebensmitteltechnik (BLT)
Publikationstyp Zeitschriftenaufsatz
Publikationsdatum 25.05.2024
Sprache Englisch
Identifikator ISSN: 2731-3654
KITopen-ID: 1000171579
Erschienen in Biotechnology for Biofuels and Bioproducts
Verlag Springer Fachmedien Wiesbaden
Band 17
Heft 1
Seiten Art.-Nr.: 67
Schlagwörter Simultaneous saccharification and fermentation, Enzymatic biocatalysis, Enzymatic esterification, Butyl butyrate, Biofuel, Coupling fermentation and enzymatic biocatalysis
Nachgewiesen in Scopus
Web of Science
Dimensions
Globale Ziele für nachhaltige Entwicklung Ziel 7 – Bezahlbare und saubere Energie
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