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CART: Carrier‐Based Actuatable and Reprogrammable Transport

Mandsberg, Nikolaj K. ORCID iD icon 1; Serna, Julian A. ORCID iD icon 1; Levkin, Pavel A. ORCID iD icon 1,2
1 Institut für Biologische und Chemische Systeme (IBCS), Karlsruher Institut für Technologie (KIT)
2 Institut für Organische Chemie (IOC), Karlsruher Institut für Technologie (KIT)

Abstract:

Remote manipulation of microcargo is essential for miniaturized automated experiments in fields such as biology, chemistry, and diagnostics, allowing efficient use of scarce, expensive, or hazardous materials. Current methods for manipulating microcargo are generally limited to droplets as cargo and rely on reduced substrate-cargo friction and special substrate-cargo interactions (electrowetting, anisotropic wetting, water-repellency, etc.) to enable cargo mobility. This limits the versatility of substrate and cargo choice. Here, CART (Carrier-based Actuatable and Reprogrammable Transport) is presented as a solution to these challenges. By introducing a carrier between the substrate and the cargo, CART physically separates them, eliminating the need to reduce substrate-cargo friction and the need for substrate-cargo matching. CART devices are easy to realize, tailor, and post-functionalize. A photo-polymerizable phase-separating resin is used to 3D-print porous carriers that are then infused with ferrofluid to make them magnetically responsive, enabling untethered cargo manipulation on both solid and liquid substrates. Using CART, various cargos can be remotely moved, rotated/mixed, inverted, and lifted, further facilitating interaction between two carriers for transferring, merging, and tunably splitting cargo. ... mehr


Verlagsausgabe §
DOI: 10.5445/IR/1000173333
Veröffentlicht am 12.08.2024
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Biologische und Chemische Systeme (IBCS)
Institut für Organische Chemie (IOC)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2024
Sprache Englisch
Identifikator ISSN: 1616-301X, 1616-3028
KITopen-ID: 1000173333
Erschienen in Advanced Functional Materials
Verlag Wiley-VCH Verlag
Seiten 2406635
Vorab online veröffentlicht am 29.07.2024
Nachgewiesen in Scopus
Dimensions
Web of Science
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