Electrochemical Synthesis of Disubstituted Alkynes from Dihydrazones

A simple, straightforward, scalable, and sustainable electrochemical transformation of dihydrazones to alkynes via anodic oxidation has been developed. The protocol operates under galvanostatic conditions in a commercially available undivided cell utilizing reusable carbon-based electrodes. This methodology enables the efficient synthesis of a broad range of alkynes with moderate to excellent yield. The successful demonstration of gram-scale synthesis, along with a consistent electrode reusability profile, underlines the synthetic utility and preparative potential of the approach.