Parallelized 61-sample inhibition screening accelerated by 19F-MRI compressed sensing
Faderl, Dilara 1; Gossert, Alvar D.; Korvink, Jan G.; MacKinnon, Neil
1 Institut für Mikrostrukturtechnik (IMT), Karlsruher Institut für Technologie (KIT)
1 Institut für Mikrostrukturtechnik (IMT), Karlsruher Institut für Technologie (KIT)
| Zugehörige Institution(en) am KIT | Institut für Mikrostrukturtechnik (IMT) |
| Publikationstyp | Forschungsdaten |
| Publikationsdatum | 05.02.2026 |
| Erstellungsdatum | 03.02.2026 |
| Identifikator | DOI: 10.35097/j2ryda8x9m31qaea KITopen-ID: 1000190182 |
| HGF-Programm | 43.35.02 (POF IV, LK 01) Functionality of Soft Matter and Biomolecular Systems |
| Lizenz | Creative Commons Namensnennung 4.0 International |
| Projektinformation | HISCORE (EU, H2020, 951459) SFB 1527; HyPERiON, 454252029 (DFG, DFG KOORD, SFB 1527_1) |
| Liesmich | This submission includes raw 19F-MRI data generated for ligand binding characterization, supported by T2-relaxation results for compound screening (IC50 determination by originLab) and reference datasets (in Excel, the hit ranking). Raw MRI data acquired for ligand binding and screening studies. The dataset includes measurements from compressed sensing experiments (capillary and honeycomb setups), reference library acquisitions for BZA, BZD, and MZA, as well as raw data from trypsin primary hit screening and strong ligand validation. Additional raw data related to a CoAD study are also included. |
| Art der Forschungsdaten | Dataset |