LowCOST‐HSQC Variants for Fast‐Pulsing High ω 1 ‐Resolved 2D Experiments
Schulze-Sünninghausen, David; Becker, Johanna; Koos, Martin R. M.; Luy, Burkhard
1
1 Institut für Organische Chemie (IOC), Karlsruher Institut für Technologie (KIT)
11 Institut für Organische Chemie (IOC), Karlsruher Institut für Technologie (KIT)
Abstract:
The LowCOST-
HSQC is a sensitivity-
enhanced HSQC version that retains unused proton polarization for subsequent scans in
correlations to low natural abundance nuclei like
13
C or
15
N. Together with fast polarization distribution via isotropic mixing, it
allows the acquisition of fast-
pulsing 2D experiments. We give a detailed introduction and comparison of three possible INEPT-
type transfer elements for the LowCOST approach—the original LowCOST, the ZIP, and a specific TIG-
BIRD element—and
evaluate various variants of the LowCOST-
HSQC.
HSQC is a sensitivity-
enhanced HSQC version that retains unused proton polarization for subsequent scans in
correlations to low natural abundance nuclei like
13
C or
15
N. Together with fast polarization distribution via isotropic mixing, it
allows the acquisition of fast-
pulsing 2D experiments. We give a detailed introduction and comparison of three possible INEPT-
type transfer elements for the LowCOST approach—the original LowCOST, the ZIP, and a specific TIG-
BIRD element—and
evaluate various variants of the LowCOST-
HSQC.
| Zugehörige Institution(en) am KIT | Institut für Organische Chemie (IOC) |
| Publikationstyp | Zeitschriftenaufsatz |
| Publikationsmonat/-jahr | 07.2026 |
| Sprache | Englisch |
| Identifikator | ISSN: 0749-1581, 1097-458X KITopen-ID: 1000198109 |
| Erschienen in | Magnetic Resonance in Chemistry |
| Verlag | John Wiley and Sons |
| Band | 64 |
| Heft | 7 |
| Seiten | 655–665 |
| Vorab online veröffentlicht am | 16.04.2026 |
| Nachgewiesen in | Scopus OpenAlex |