[{"type":"article-journal","title":"Magnetic Lenz lenses improve the limit-of-detection in nuclear magnetic resonance","issued":{"date-parts":[["2017"]]},"volume":"12","issue":"8","page":"Art. Nr.: e0182779","container-title":"PLoS one","DOI":"10.1371\/journal.pone.0182779","author":[{"family":"Spengler","given":"N."},{"family":"While","given":"P. T."},{"family":"Meissner","given":"M. V."},{"family":"Wallrabe","given":"U."},{"family":"Korvink","given":"J. G."}],"publisher":"Public Library of Science (PLoS)","ISSN":"1932-6203","abstract":"A high NMR detection sensitivity is indispensable when dealing with mass and volume-limited\r\nsamples, or whenever a high spatial resolution is required. The use of miniaturised RF\r\ncoils is a proven way to increase sensitivity, but situations may arise where space restrictions\r\ncould prevent the use of a small resonant coil, e.g., in the interior of the smallest practicable\r\nmicro-coils. We present the use of magnetic lenses, denoted as Lenz lenses due to\r\ntheir working principle, to focus the magnetic flux of an RF coil into a smaller volume and\r\nthereby locally enhance the sensitivity of the NMR experiment\u00d0at the expense of the total\r\nsensitive volume. Besides focusing, such lenses facilitate re-guiding or re-shaping of magnetic\r\nfields much like optical lenses do with light beams. For the first time we experimentally\r\ndemonstrate the use of Lenz lenses in magnetic resonance and provide a compact mathematical\r\ndescription of the working principle. Through simulations we show that optimal\r\narrangements can be found.","kit-publication-id":"1000073936"}]