Multiscale Modeling of the Ventricles: From Cellular Electrophysiology to Body Surface Electrocardiograms
Abstract:
This work is focused on different aspects within the loop of multiscale modeling:
On the cellular level, effects of adrenergic regulation and the Long-QT syndrome have been investigated.
On the organ level, a model for the excitation conduction system was developed and the role of electrophysiological heterogeneities was analyzed.
On the torso level a dynamic model of a deforming heart was created and the effects of tissue conductivities on the solution of the forward problem were evaluated.
On the cellular level, effects of adrenergic regulation and the Long-QT syndrome have been investigated.
On the organ level, a model for the excitation conduction system was developed and the role of electrophysiological heterogeneities was analyzed.
On the torso level a dynamic model of a deforming heart was created and the effects of tissue conductivities on the solution of the forward problem were evaluated.
| Zugehörige Institution(en) am KIT | Institut für Biomedizinische Technik (IBT) |
| Publikationstyp | Hochschulschrift |
| Publikationsjahr | 2011 |
| Sprache | Englisch |
| Identifikator | ISBN: 978-3-86644-714-1 ISSN: 1864-5933 urn:nbn:de:0072-238862 KITopen-ID: 1000023886 |
| Verlag | KIT Scientific Publishing |
| Umfang | XIII, 248 S. |
| Serie | Karlsruhe transactions on biomedical engineering / Ed.: Karlsruhe Institute of Technology / Institute of Biomedical Engineering ; 13 |
| Art der Arbeit | Dissertation |
| Fakultät | Fakultät für Elektrotechnik und Informationstechnik (ETIT) |
| Institut | Institut für Biomedizinische Technik (IBT) |
| Prüfungsdaten | 9.06.2011 |
| Schlagwörter | Multiscale Modeling, Forward Calculation, Cardiac Electrophysiology, Electrophysiological Heterogeneities |
| Referent/Betreuer | Dössel, O. |