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DOI: 10.5445/KSP/1000023886
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Multiscale Modeling of the Ventricles: From Cellular Electrophysiology to Body Surface Electrocardiograms

Keller, David Urs Josef

Abstract:
This work is focused on different aspects within the loop of multiscale modeling:
On the cellular level, effects of adrenergic regulation and the Long-QT syndrome have been investigated.
On the organ level, a model for the excitation conduction system was developed and the role of electrophysiological heterogeneities was analyzed.
On the torso level a dynamic model of a deforming heart was created and the effects of tissue conductivities on the solution of the forward problem were evaluated.


Zugehörige Institution(en) am KIT Institut für Biomedizinische Technik (IBT)
Publikationstyp Hochschulschrift
Jahr 2011
Sprache Englisch
Identifikator ISBN: 978-3-86644-714-1
ISSN: 1864-5933
URN: urn:nbn:de:0072-238862
KITopen ID: 1000023886
Verlag KIT Scientific Publishing, Karlsruhe
Umfang XIII, 248 S.
Serie Karlsruhe transactions on biomedical engineering / Ed.: Karlsruhe Institute of Technology / Institute of Biomedical Engineering ; 13
Abschlussart Dissertation
Fakultät Fakultät für Elektrotechnik und Informationstechnik (ETIT)
Institut Institut für Biomedizinische Technik (IBT)
Prüfungsdaten 9.06.2011
Referent/Betreuer Prof. O. Dössel
Schlagworte Multiscale Modeling, Forward Calculation, Cardiac Electrophysiology, Electrophysiological Heterogeneities
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