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URN: urn:nbn:de:swb:90-287959

Numerical Simulation of Particle Deposition in the Human Lungs

Gengenbach, Thomas

Abstract:
We model, simulate and calculate breathing and particle depositions in the human lungs. We review the theory and discretization of fluid mechanics, the anatomy, physiology and measuring methods of lungs. A new model is introduced and investigated with a sensitivity analysis using the singular value decomposition. Particle depositions are simulated in patient-specific and schematized human lungs and compared to the particle deposition in a multiplicative model of subsequent bifurcations.


Zugehörige Institution(en) am KIT Institut für Angewandte und Numerische Mathematik (IANM)
Publikationstyp Hochschulschrift
Jahr 2012
Sprache Englisch
Identifikator URN: urn:nbn:de:swb:90-287959
KITopen ID: 1000028795
Verlag Karlsruhe
Abschlussart Dissertation
Fakultät Fakultät für Mathematik (MATH)
Institut Institut für Angewandte und Numerische Mathematik (IANM)
Prüfungsdaten 27.06.2012
Referent/Betreuer Prof. V. Heuveline
Schlagworte human lungs, particle deposition, sensitivity analysis, fluid flow simulations, mathematical modeling
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