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URN: urn:nbn:de:swb:90-287959

Numerical Simulation of Particle Deposition in the Human Lungs

Gengenbach, Thomas

We model, simulate and calculate breathing and particle depositions in the human lungs. We review the theory and discretization of fluid mechanics, the anatomy, physiology and measuring methods of lungs. A new model is introduced and investigated with a sensitivity analysis using the singular value decomposition. Particle depositions are simulated in patient-specific and schematized human lungs and compared to the particle deposition in a multiplicative model of subsequent bifurcations.

Zugehörige Institution(en) am KIT Institut für Angewandte und Numerische Mathematik (IANM)
Publikationstyp Hochschulschrift
Jahr 2012
Sprache Englisch
Identifikator KITopen ID: 1000028795
Verlag Karlsruhe
Abschlussart Dissertation
Fakultät Fakultät für Mathematik (MATH)
Institut Institut für Angewandte und Numerische Mathematik (IANM)
Prüfungsdaten 27.06.2012
Referent/Betreuer Prof. V. Heuveline
Schlagworte human lungs, particle deposition, sensitivity analysis, fluid flow simulations, mathematical modeling
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