A unique role of E-cadherin among the cadherin family members co-expressed in the neural crest?
Abstract:
In the present work, quantitative analysis of six different cadherin superfamily members provides a novel cadherin expression profile in Xenopus cranial neural crest (CNC) cells. Interestingly, E-cadherin, together with XB/C-cadherins and PAPC are identified for the first time in CNC cells. Furthermore, knockdown analysis of E-cadherin allocates a novel function of this cadherin in mediating CNC migration.
| Zugehörige Institution(en) am KIT | Zoologisches Institut (ZOO) |
| Publikationstyp | Hochschulschrift |
| Publikationsjahr | 2014 |
| Sprache | Englisch |
| Identifikator | urn:nbn:de:swb:90-424336 KITopen-ID: 1000042433 |
| Verlag | Karlsruher Institut für Technologie (KIT) |
| Art der Arbeit | Dissertation |
| Fakultät | Fakultät für Chemie und Biowissenschaften (CHEM-BIO) |
| Institut | Zoologisches Institut (ZOO) |
| Prüfungsdaten | 18.07.2014 |
| Schlagwörter | E-cadherin, neural crest |
| Referent/Betreuer | Wedlich, D. |