Layered Modeling and Simulation of Complex Biotechnological Processes - Optimizing Rhamnolipid Production by Pseudomonas aeruginosa during Cultivation in a Bioreactor
Abstract:
In this thesis, a model for the regulation of rhamnolipid production and data obtained from metabolic balancing were combined with a process model on a bioreactor scale. The model was used to derive an optimized process control stategy for enhanced product formation. This thesis provides a missing piece in a puzzle for knowledge-based strategies for enhanced rhamnolipid formation.
| Zugehörige Institution(en) am KIT | Institut für Bio- und Lebensmitteltechnik (BLT) |
| Publikationstyp | Hochschulschrift |
| Publikationsjahr | 2014 |
| Sprache | Englisch |
| Identifikator | urn:nbn:de:swb:90-443335 KITopen-ID: 1000044333 |
| Verlag | Karlsruher Institut für Technologie (KIT) |
| Art der Arbeit | Dissertation |
| Fakultät | Fakultät für Chemieingenieurwesen und Verfahrenstechnik (CIW) |
| Institut | Institut für Bio- und Lebensmitteltechnik (BLT) |
| Prüfungsdaten | 21.11.2014 |
| Schlagwörter | Layered Modeling, Rhamnolipid, Pseudomonas aeruginosa |
| Referent/Betreuer | Syldatk, C. |