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Xanthone dimers: a compound family which is both common and privileged

Wezeman, Tim; Bräse, Stefan; Masters, Kye-Simeon

Covering: up to 2014 Xanthone dimers are a widespread, structurally-diverse family of natural products frequently found in plants, fungi and lichens. They feature an intriguing variety of linkages between the component xanthones (benzannulated chromanones). These synthetically elusive secondary metabolites are of great interest due to their broad array of bioactivities, which has led to the xanthones being designated as `privileged structures`. We seek herein to give an overview of all reliably-described xanthone dimers, their structures, occurrence, and the bioactivities established to date. The possible biosynthetic pathways leading to members of this family are also discussed in light of our current knowledge.

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Volltext §
DOI: 10.5445/IR/1000046415
DOI: 10.1039/C4NP00050A
Zitationen: 68
Web of Science
Zitationen: 67
Zugehörige Institution(en) am KIT Institut für Organische Chemie (IOC)
Institut für Toxikologie und Genetik (ITG)
Publikationstyp Zeitschriftenaufsatz
Jahr 2015
Sprache Englisch
Identifikator ISSN: 0265-0568
KITopen-ID: 1000046415
HGF-Programm 47.01.01 (POF III, LK 01)
Erschienen in Natural Product Reports
Band 32
Heft 1
Seiten 6-28
Bemerkung zur Veröffentlichung RSC geförderter Open Access-Artikel
Nachgewiesen in Scopus
Web of Science
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