KIT | KIT-Bibliothek | Impressum | Datenschutz

Xanthone dimers: a compound family which is both common and privileged

Wezeman, Tim 1; Bräse, Stefan 1,2; Masters, Kye-Simeon
1 Institut für Organische Chemie (IOC), Karlsruher Institut für Technologie (KIT)
2 Institut für Toxikologie und Genetik (ITG), Karlsruher Institut für Technologie (KIT)

Abstract:

Covering: up to 2014 Xanthone dimers are a widespread, structurally-diverse family of natural products frequently found in plants, fungi and lichens. They feature an intriguing variety of linkages between the component xanthones (benzannulated chromanones). These synthetically elusive secondary metabolites are of great interest due to their broad array of bioactivities, which has led to the xanthones being designated as `privileged structures`. We seek herein to give an overview of all reliably-described xanthone dimers, their structures, occurrence, and the bioactivities established to date. The possible biosynthetic pathways leading to members of this family are also discussed in light of our current knowledge.


Volltext §
DOI: 10.5445/IR/1000046415
Originalveröffentlichung
DOI: 10.1039/C4NP00050A
Scopus
Zitationen: 147
Web of Science
Zitationen: 144
Dimensions
Zitationen: 156
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Organische Chemie (IOC)
Institut für Toxikologie und Genetik (ITG)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2015
Sprache Englisch
Identifikator ISSN: 0265-0568
urn:nbn:de:swb:90-464159
KITopen-ID: 1000046415
HGF-Programm 47.01.01 (POF III, LK 01) Biol.Netzwerke u.Synth.Regulat. ITG+ITC
Erschienen in Natural Product Reports
Verlag Royal Society of Chemistry (RSC)
Band 32
Heft 1
Seiten 6-28
Bemerkung zur Veröffentlichung RSC geförderter Open Access-Artikel
Nachgewiesen in Scopus
Dimensions
Web of Science
KIT – Die Forschungsuniversität in der Helmholtz-Gemeinschaft
KITopen Landing Page