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Objective assessment of motor and gait parameters of patients with multiple sclerosis

Shammas, Layal

Abstract (englisch):
Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system. It affects approximately 400.000 individuals in Europe and about 2.5 million worldwide. Clinical symptoms of MS are highly variable and depend on the localization of lesions in the brain and spinal cord. Patients with chronic progressive neurological diseases such as MS typically show a decrease of physical activity as compared with healthy individuals. Approximately 75 to 80 percent of patients with MS (PwMS) experience walking and physical activity impairment in early stages of the disease. Therefore, walking impairment is considered as a hallmark symptom as this may have a significant impact on different daily activities. Moreover, an indirect association between overall MS symptoms and physical activity was found.
Several studies investigated the walking ability and physical activity under free-living conditions in PwMS, as this may provide significant information to predict the patient’s health status. Different methods have been used for this purpose, including subjective approaches like self-report, questionnaires or diary methods. Although these methods are inexpensive and can easily be employed preferably in large scale studies, they are prone to error due to memory failure and other kind of misreporting. ... mehr

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Volltext §
DOI: 10.5445/IR/1000084201
Veröffentlicht am 06.07.2018
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Technik der Informationsverarbeitung (ITIV)
Publikationstyp Hochschulschrift
Publikationsjahr 2018
Sprache Englisch
Identifikator urn:nbn:de:swb:90-842014
KITopen-ID: 1000084201
Verlag KIT, Karlsruhe
Umfang 198 S.
Art der Arbeit Dissertation
Fakultät Fakultät für Elektrotechnik und Informationstechnik (ETIT)
Institut Institut für Technik der Informationsverarbeitung (ITIV)
Prüfungsdatum 15.02.2018
Referent/Betreuer Prof. W. Stork
Schlagwörter Multiple Sclerosis, Gait parameters, Physical activity, Monitoring System, Home-based, Objective assessment
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