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Toxicity of fine and quasi-ultrafine particles: focus on the effects of extractable and non-extractable matter fractions

Badran, Ghidaa; Ledoux, Frédéric; Verdin, Anthony; Abbas, Imane; Roumie, Mohamed; Genevray, Paul; Lo Cuicide, Jean-Marc; Garcon, Guillaume; Courcot, Dominique

Abstract:
Air pollution represents today one of the major risk factors for human health. An important part of this threat is due to the presence in the atmosphere of fine particulate matter (PM$_{2.5}$). PM$_{2.5}$ forms a heterogeneous mixture of inorganic pollutants (metals, ions…), organic pollutants (volatile organic compounds (VOC), polycyclic aromatic hydrocarbons (PAHs), dioxins, polychlorobiphenyls (PCBs)…), and biological contaminants (pollen, bacteria, fungi…). To date many studies have demonstrated the toxicity of PAHs and some metals, but so far, no study has been able to clearly attribute the toxicological effects observed to a class of pollutants. Therefore, this study aims to determine the physicochemical characteristics of PM$_{2.5-0.3}$ and PM$_{0,3}$ and to compare the toxicity of native PM$_{2.5-0.3}$, organic fractions of fine (EOM$_{2.5-0.3}$) and quasi ultrafine particles (OEM$_{0.3}$), and PM$_{2.5-0.3}$ freed from this organic fraction (dPM$_{2.5-0.3}$) on BEAS-2B cells in culture. Fine and quasi-ultrafine particles were sampled in the southern suburb of Beirut, Lebanon. Chemical characterization showed that quasi-ultrafine particles were about 40 times more concentrated in PAHs than fines one suggesting a significant influence of anthropogenic activities and combustion sources (industries, road traffic and electric generators) on the emission of quasi-ultrafine particles. ... mehr

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Volltext §
DOI: 10.5445/IR/1000096841
Veröffentlicht am 25.07.2019
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Meteorologie und Klimaforschung - Atmosphärische Aerosolforschung (IMK-AAF)
Publikationstyp Vortrag
Publikationsdatum 16.02.2019
Sprache Englisch
Identifikator KITopen-ID: 1000096841
Veranstaltung 7th International Symposium on Ultrafine Particles, Air Quality and Climate (2019), Brüssel, Belgien, 15.05.2019 – 16.05.2019
Schlagwörter fine particles, quasi-ultrafine particles, organic extractable matter, metabolic activation, genotoxicity
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