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Influence of ECG Lead reduction techniques for extracellular potassium and calcium concentration estimation

Mesa, M. H. 1; Pilia, N. 1; Dössel, O. 1; Loewe, A. ORCID iD icon 1
1 Institut für Biomedizinische Technik (IBT), Karlsruher Institut für Technologie (KIT)


Chronic kidney disease (CKD) affects 13% of the worldwide population and end stage patients often receive haemodialysis treatment to control the electrolyte concentrations. The cardiovascular death rate increases by 10% - 30% in dialysis patients than in general population. To analyse possible links between electrolyte concentration variation and cardiovascular diseases, a continuous noninvasive monitoring tool enabling the estimation of potassium and calcium concentration from features of the ECG is desired. Although the ECG was shown capable of being used for this purpose, the method still needs improvement. In this study, we examine the influence of lead reduction techniques on the estimation results of serum calcium and potassium concentrations. We used simulated 12 lead ECG signals obtained using an adapted Himeno et al. model. Aiming at a precise estimation of the electrolyte concentrations, we compared the estimation based on standard ECG leads with the estimation using linearly transformed fusion signals. The transformed signals were extracted from two lead reduction techniques: principle component analysis PCA) and maximum amplitude transformation (MaxAmp). ... mehr

Verlagsausgabe §
DOI: 10.5445/IR/1000098760
Veröffentlicht am 09.10.2019
DOI: 10.1515/cdbme-2019-0018
Zitationen: 2
Zitationen: 3
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Biomedizinische Technik (IBT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2019
Sprache Englisch
Identifikator ISSN: 2364-5504
KITopen-ID: 1000098760
Erschienen in Current directions in biomedical engineering
Verlag De Gruyter
Band 5
Heft 1
Seiten 69-72
Vorab online veröffentlicht am 18.09.2019
Schlagwörter ECG, PCA, lead reduction techniques, cardiac signals, ionic concentrations
Nachgewiesen in Dimensions
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