Strong evidence exists that fitness is a physical health resource, which serves to protect one’s health. There is still uncertainty about which fitness level provides the best health outcome and which measurements can be used for analyzing this question. This cross-sectional study analyzed 462 (64.07% female) German middle-aged adults regarding their fitness status, physical activity (Non-Exercise test), body composition (Body Mass Index) and heart-related health status. Motor tests were used to measure the health-related fitness status. The heart-related health status was surveyed by questionnaire and diagnosis was done in part by a physician. Relationships between risk factors and fitness factors are visible during the correlative analysis. They are substantially more visible in the differentiation of people with and without risks. People with low fitness show noticeable risks in activity, Body Mass Index and heart-related health. People with high fitness show health resources for activity, Body Mass Index and heart-related health. This study points out that all fitness dimensions influence one’s heart-related health in a positive way. ... mehrFitness is measured objectively and includes all health-related fitness dimensions such as endurance, strength, coordination and flexibility. Apart from this standardization, we ask for more longitudinal studies and more objective health measurements.