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Evaluation of semi-supervised learning using sparse labeling to segment cell nuclei

Bruch, Roman ORCID iD icon; Rudolf, Rüdiger; Mikut, Ralf ORCID iD icon 1; Reischl, Markus ORCID iD icon 1
1 Institut für Automation und angewandte Informatik (IAI), Karlsruher Institut für Technologie (KIT)


The analysis of microscopic images from cell cultures plays an important role in the development of drugs. The segmentation of such images is a basic step to extract the viable information on which further evaluation steps are build. Classical image processing pipelines often fail under heterogeneous conditions. In the recent years deep neuronal networks gained attention due to their great potentials in image segmentation. One main pitfall of deep learning is often seen in the amount of labeled data required for training such models. Especially for 3D images the process to generate such data is tedious and time consuming and thus seen as a possible reason for the lack of establishment of deep learning models for 3D data. Efforts have been made to minimize the time needed to create labeled training data or to reduce the amount of labels needed for training. In this paper we present a new semisupervised training method for image segmentation of microscopic cell recordings based on an iterative approach utilizing unlabeled data during training. This method helps to further reduce the amount of labels required to effectively train deep learning models for image segmentation. ... mehr

Verlagsausgabe §
DOI: 10.5445/IR/1000128498
Veröffentlicht am 10.02.2021
DOI: 10.1515/cdbme-2020-3103
Zitationen: 2
Zitationen: 2
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Automation und angewandte Informatik (IAI)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2020
Sprache Englisch
Identifikator ISSN: 2364-5504
KITopen-ID: 1000128498
HGF-Programm 47.01.02 (POF III, LK 01) Biol.Netzwerke u.Synth.Regulat. IAI
Erschienen in Current directions in biomedical engineering
Verlag De Gruyter
Band 6
Heft 3
Seiten Art.Nr. 20203103
Vorab online veröffentlicht am 01.09.2020
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