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DNA-templated control of chirality and efficient energy transport in supramolecular DNA architectures with aggregation-induced emission

Ucar, Hülya 1; Wagenknecht, Hans-Achim 1
1 Institut für Organische Chemie (IOC), Karlsruher Institut für Technologie (KIT)

Two conjugates of tetraphenylethylene with D-2′-deoxyuridine (1D) and L-2′-deoxyuridine (1L) were synthesized to construct new supramolecular DNA-architectures by self-assembly. The non-templated assemblies of 1D and 1L show strong aggregation-induced emission and their chirality is exclusively controlled by the configuration of their sugar part. In contrast, the chirality of the DNA-templated assemblies is governed by the configuration of the DNA, and there is no configuration-selective binding of 1D to D-A$_{20}$ and 1L to L-A$_{20}$. The quantum yield of the assembly of 1D along the single-stranded DNA A$_{20}$ is 0.40; approximately every second available binding site on the DNA template is occupied by 1D. The strong aggregation-induced emission of these DNA architectures can be efficiently quenched and the excitation energy can be transported to Atto dyes at the 5′-terminus. A multistep energy transport “hopping” precedes the final energy transfer to the terminal acceptor. The building block 1D promotes this energy transport as stepping stones. This was elucidated by reference DNA double strands in which 1D was covalently incorporated at two distinct sites in the sequences, one near the Atto dye, and one farther away. ... mehr

Verlagsausgabe §
DOI: 10.5445/IR/1000135467
Veröffentlicht am 30.04.2022
DOI: 10.1039/d1sc02351a
Zitationen: 2
Web of Science
Zitationen: 2
Zitationen: 2
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Organische Chemie (IOC)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2021
Sprache Englisch
Identifikator ISSN: 2041-6520, 2041-6539
KITopen-ID: 1000135467
Erschienen in Chemical science
Verlag Royal Society of Chemistry (RSC)
Band 29
Seiten 10048-10053
Vorab online veröffentlicht am 21.06.2021
Nachgewiesen in Dimensions
Web of Science
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