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Effects of a 16-week multimodal exercise program on activities of daily living in institutionalized individuals with dementia: A multicenter randomized controlled trial [Auswirkungen eines 16-wöchigen multimodalen Trainingsprogramms auf die Aktivitäten des täglichen Lebens bei Heimbewohnern mit Demenz: Eine multizentrische randomisierte kontrollierte Studie]

Bezold, Jelena; Trautwein, Sandra; Barisch-Fritz, Bettina ORCID iD icon; Scharpf, Andrea; Krell-Roesch, Janina ORCID iD icon; Nigg, Claudio R.; Woll, Alexander ORCID iD icon

Abstract:

We aimed to examine the effects of a 16-week multimodal exercise program (MEP) on activities of daily living (ADL) in individuals with dementia (IWD). Furthermore, we investigated the participants’ individual response to the MEP and whether baseline cognitive and motor performance explain ADL performance. We conducted a multicenter randomized controlled trial (RCT) involving 319 participants aged ≥ 65 years with mild to moderate dementia. ADL were assessed at baseline and after the 16-week intervention using the Barthel Index (BI), the Erlangen Test of Activities of Daily Living (E-ADL) and the 7‑item Physical Performance Test (PPT-7). We additionally assessed cognitive and motor performance using standardized and validated assessments. Intervention effects were examined through two-factor analysis of variance with repeated measurements applying a per protocol and an intention-to-treat analysis. We compared baseline cognitive and motor performance between positive-responders (positive-R), non-responders (non-R), and negative-responders (negative-R) and examined cognitive and motor performance as potential cofounders of ADL by conducting multiple regression analyses. ... mehr


Verlagsausgabe §
DOI: 10.5445/IR/1000139377
Veröffentlicht am 29.10.2021
Originalveröffentlichung
DOI: 10.1007/s12662-021-00760-4
Scopus
Zitationen: 6
Dimensions
Zitationen: 8
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Sport und Sportwissenschaft (IfSS)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2021
Sprache Englisch
Identifikator ISSN: 2509-3142, 0342-2380, 1868-1069, 2509-3150
KITopen-ID: 1000139377
Erschienen in German Journal of Exercise and Sport Research
Verlag Springer-Verlag
Band 51
Seiten 506–517
Vorab online veröffentlicht am 14.10.2021
Nachgewiesen in Scopus
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