Human genome editing. TAB-Fokus
Albrecht, Steffen; König, Harald
; Sauter, Arnold
; Sauter, Arnold
Abstract:
- Genome editing, a new set of methods of genetic engineering, enables targeted interventions in somatic as well as in germline cells in humans.
- Genome editing can help improve somatic gene therapies and expand their scope of application. Initial approaches are currently being tested in clinical trials.
- Research and innovation policy impulses are needed for the development of gene- and cell-based therapies, particularly for rare diseases. The costs of the procedureslikely will remain high. Accordingly, novel reimbursement models are needed.
- Unresolved health risks and fundamental ethical issues preclude a clinical application of germline interventions.
- Genome editing can help improve somatic gene therapies and expand their scope of application. Initial approaches are currently being tested in clinical trials.
- Research and innovation policy impulses are needed for the development of gene- and cell-based therapies, particularly for rare diseases. The costs of the procedureslikely will remain high. Accordingly, novel reimbursement models are needed.
- Unresolved health risks and fundamental ethical issues preclude a clinical application of germline interventions.
| Zugehörige Institution(en) am KIT | Institut für Technikfolgenabschätzung und Systemanalyse (ITAS) |
| Publikationstyp | Sonstiges |
| Publikationsmonat/-jahr | 09.2021 |
| Sprache | Englisch |
| Identifikator | ISSN: 2364-2645 KITopen-ID: 1000141085 |
| HGF-Programm | 46.24.02 (POF IV, LK 01) Conceptual and Methodological Research |
| Verlag | Büro für Technikfolgen-Abschätzung beim Deutschen Bundestag (TAB) |
| Serie | TAB-Fokus ; 30 |
| Externe Relationen | Siehe auch |
| Schlagwörter | genetic engineering; technology assessment |
| Relationen in KITopen |