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Human genome editing. TAB-Fokus

Albrecht, Steffen; König, Harald ORCID iD icon; Sauter, Arnold


- Genome editing, a new set of methods of genetic engineering, enables targeted interventions in somatic as well as in germline cells in humans.
- Genome editing can help improve somatic gene therapies and expand their scope of application. Initial approaches are currently being tested in clinical trials.
- Research and innovation policy impulses are needed for the development of gene- and cell-based therapies, particularly for rare diseases. The costs of the procedureslikely will remain high. Accordingly, novel reimbursement models are needed.
- Unresolved health risks and fundamental ethical issues preclude a clinical application of germline interventions.

Volltext §
DOI: 10.5445/IR/1000141085
Veröffentlicht am 14.12.2021
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Technikfolgenabschätzung und Systemanalyse (ITAS)
Publikationstyp Sonstiges
Publikationsmonat/-jahr 09.2021
Sprache Englisch
Identifikator ISSN: 2364-2645
KITopen-ID: 1000141085
HGF-Programm 46.24.02 (POF IV, LK 01) Conceptual and Methodological Research
Verlag Büro für Technikfolgen-Abschätzung beim Deutschen Bundestag (TAB)
Serie TAB-Fokus ; 30
Externe Relationen Siehe auch
Schlagwörter genetic engineering; technology assessment
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KIT – Die Forschungsuniversität in der Helmholtz-Gemeinschaft
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